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所在位置:所有产品 > 抗体抗原 > 一抗 > IRE1/ERN1抗体
IRE1/ERN1抗体图片
产品货号:
Z37420
中文名称:
IRE1/ERN1抗体
英文名称:
Anti-IRE1/ERN1 Antibody (Clone#9F2)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-IRE1/ERN1 Antibody (Clone#9F2)
指标别名ERN1;hIRE1p;Inositol requiring protein 1;IRE1;Ire1 alpha;IRE1;ERN1;IRE1P;IRE1α
克隆性Monoclonal
检验物种human
应用范围WB,IHC,ELISA
基因名称ERN1
克隆号9F2
抗体来源Mouse
抗体类型IgG
免疫原Purified recombinant fragment of human IRE1alpha (aa282-433) expressed in E.Coli.
计算分子量110KD
成分Ascitic fluid containing 0.03% sodium azide.
纯化方式Affinity purification
浓度1mg/mL
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) is an enzyme that in humans is encoded by the ERN1 gene.This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1.The encoded protein contains two functional catalytic domains,a serine/threonine-protein kinase domain and an endoribonuclease domain.This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR).The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins,regulating protein synthesis and activating molecular chaperones.This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1.
Uniprot IDO75460
基因名全称Serine/threonine-protein kinase/endoribonuclease IRE1
蛋白名全称Serine/threonine-protein kinase/endoribonuclease IRE1
推荐稀释比WB 1:500~1:2000
IHC 1:200~1:1000
ELISA 1:10000

相关搜索:IRE1/ERN1抗体IRE1抗体ERN1单抗Anti-IRE1/ERN1 Antibody (Clone#9F2)
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