产品货号:
Z37420
中文名称:
IRE1/ERN1抗体
英文名称:
Anti-IRE1/ERN1 Antibody (Clone#9F2)
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-IRE1/ERN1 Antibody (Clone#9F2) |
指标别名 | ERN1;hIRE1p;Inositol requiring protein 1;IRE1;Ire1 alpha;IRE1;ERN1;IRE1P;IRE1α |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ELISA |
基因名称 | ERN1 |
克隆号 | 9F2 |
抗体来源 | Mouse |
抗体类型 | IgG |
免疫原 | Purified recombinant fragment of human IRE1alpha (aa282-433) expressed in E.Coli. |
计算分子量 | 110KD |
成分 | Ascitic fluid containing 0.03% sodium azide. |
纯化方式 | Affinity purification |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) is an enzyme that in humans is encoded by the ERN1 gene.This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1.The encoded protein contains two functional catalytic domains,a serine/threonine-protein kinase domain and an endoribonuclease domain.This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR).The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins,regulating protein synthesis and activating molecular chaperones.This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. |
Uniprot ID | O75460 |
基因名全称 | Serine/threonine-protein kinase/endoribonuclease IRE1 |
蛋白名全称 | Serine/threonine-protein kinase/endoribonuclease IRE1 |
推荐稀释比 | WB 1:500~1:2000 IHC 1:200~1:1000 ELISA 1:10000 |
相关搜索:IRE1/ERN1抗体,IRE1抗体,ERN1单抗,Anti-IRE1/ERN1 Antibody (Clone#9F2)